Analysis of Biological Networks (BE.440)

By MIT OpenCourseWare · Published by MIT Open Learning · Language: English
Source: MIT Open Learning Format: Course materials Undergraduate / College
Engineering Biology Biological Engineering Science & Math MIT OpenCourseWare MIT OpenCourseWare

"Analysis of Biological Networks (BE.440)" is a Course materials drawn from MIT Open Learning and catalogued under Chemistry for Undergraduate / College. From the source: This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. Examples of processes to be… Slide Collection preserves the upstream link, the original creator credit and the licensing terms; download the file to use it in a classroom, study group or revision plan.

About this presentation

This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. Examples of processes to be studied include chemotaxis, the fixation of nitrogen into organic biological molecules, growth factor and hormone mediated signaling cascades, and signaling cascades leading to cell death in response to DNA damage. In each case, the availability of a resource, or the presence of a stimulus, results in some biochemical pathways being turned on while others are turned off. The course examines the dynamic aspects of these processes and details how biochemical mechanistic themes impinge on molecular/cellular/tissue/organ-level functions. Chemical and quantitative views of the interplay of multiple pathways as biological networks are emphasized. Student work culminates in the preparation of a unique grant application in an area of biological networks.

How to study this deck

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Five questions to test your understanding

  1. What is the single most important claim on the first three slides, and what evidence is offered for it?
  2. Which slide could you remove without losing the argument? Which slide is load-bearing?
  3. Where does the deck switch from definitions to applications? Mark that transition.
  4. What would a student who already disagreed with the conclusion need to see to be convinced?
  5. Which two slides, if combined, would give the clearest one-slide summary of the whole deck?

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